STAT3 and glioblastoma: STAT3 co-expressed genes from the Rembrandt patient database (Fig. 1a, middle panel) that displayed inverse expression upon STAT3 KD in patient-derived GBM-propagating cells (GPCs; Fig. 1a, left panel) were identified to form the STAT3 “functionally tuned” gene signature (Fig. 1a, right panel)18.