WWP2 and familial dilated cardiomyopathy: In both LV (DCM) and RV (rTOF) fibrotic hearts, we observed a positive and significant shift in the distribution of the correlations between WWP2 and the expression of the hECM-network genes (Fig. 2d, e), suggesting a positive association between WWP2 cardiac expression and the hECM-network genes in disease.