AGT and familial dilated cardiomyopathy: Bulk RNA-seq analysis in AngII-treated WT (n = 8) and WWP2Mut/Mut mice (n = 8) hearts revealed that the mouse orthologs of the hECM-network genes detected in DCM heart have a different co-expression pattern with increased gene co-expression in WT compared with WWP2Mut/Mut (P = 0.003 by permutation test, Fig. 3i).