NOTCH1 and acute lymphoblastic leukemia: Concomitant to absence of 5′ Notch1 deletions, the analysis of Notch1DECRREE-derived T-ALL suggested an increase in Notch1 HD-domain mutations and thus the alignment of the mouse and human Notch1 mutational spectrums, although a greater sample size is needed to unequivocally support this notion.