Among these loci examined, carrier of rs6983267GG in CCAT2 were more susceptible to HCC, with the OR and AOR being 1.532 (95% CI, 1.103–2.129; p = 0.011) and 1.627 (95% CI, 1.120–2.265; p = 0.033), respectively. Here, CCAT2 is linked to hepatocellular carcinoma.