A multivariate analysis revealed that baseline sST2 level in effluent was independently associated with risk of PDF development after adjusting for peritoneal transport parameters (weekly Kt/V and D/P Cr) and clinical covariates such as age, sex, BMI, DM, hypertension, haemoglobin, serum albumin and Cr (Table 2). The gene discussed is ALB; the disease is diabetes mellitus.