MAP2K7 and pulmonary embolism: Analysis revealed that therapy with BRAF and MEK inhibitors was associated with a risk of pulmonary embolism (RR, 4.36; 95% CI, 1.23-15.44; P = .02; I2 = 0%), with 2.2% of patients from the BRAF and MEK group developing pulmonary embolism compared with 0.4% of the BRAF inhibitor monotherapy group.