In patients with T2D, there was no significant difference in the observed mean (SD) total daily basal insulin dose at 12 months [35.9 U/d (33.0); median 26.1; Q1 to Q3, 18.0 to 42.0] vs baseline [37.5 (33.9); median 26.9; Q1 to Q3, 18.0 to 43.0; ETD −0.09 U/d; 95% CI, −1.48 to 1.30] (Fig. 6A). Here, INS is linked to type 2 diabetes mellitus.