The renin‐angiotensin‐aldosterone system (RAAS) plays an important role in the regulation of blood pressure, as evidenced by many genetic forms of human hypertension that map to the RAAS as well by the fact that blockers of this system are frequently used in the treatment of hypertension (Lifton et al. 2001a; Te Riet et al. 2015). The gene discussed is REN; the disease is hypertensive disorder.