BTK and infection: Both specific antibodies and inhibitors, including LFM‐A13 and ibrutinib, can promote the death of HIV‐1‐infected cells and decrease the virus titre markedly.32 Similarly, in murine leukaemia virus (MuLV)‐infected Xid mice with defective Btk signalling, the progression of murine acquired immunodeficiency syndrome (MAIDS) is delayed, including abnormal lymphoproliferation and severe immunosuppression.33 The studies mentioned above indicated that inhibition of Btk signalling promotes virus clearance and affects symptomatic phenotypes after infection with HIV or MvLV.