In our study we observed that the median RANTES concentration was several times higher (approximately 3-fold) in patients with both AMI and SA, as compared to those in the control group, whereas the median CCL2 was only slightly higher in both groups of patients with cardiovascular disease compared to control subjects, which may indicate that the circulating RANTES concentration reflects the presence of the atherosclerotic lesions better than CCL2. This evidence concerns the gene CCL2 and cardiovascular disorder.