Results of one earlier study hinted, comparable to ours, toward a diagnostic value of DLL1 for infection: By assessing sDLL1 levels in cerebrospinal fluid of patients with HIV with suspected Mycobacterium tuberculosis infection, the researchers found a cut-off value of 1.15 ng/ml associated with an excellent specificity of 98%, but a low sensitivity of only 32% (Bahr et al., 2018). Here, DLL1 is linked to infection.