We therefore divided patients into different groups by age, tumor size, ER status, PR status, HER-2 status, Ki-67 index (Ki-67 ≤20% was considered as low Ki-67 index, Ki-67 >20% was considered as high Ki-67 index), lymph node metastasis, pathological grade and cTNM stage according to the medical records with stratified expression level of ARHGAP10. The gene discussed is ERBB2; the disease is neoplasm.