The most shared rewiring hubs are BUB1B (brain, lung-adeno, kidney-clear, kidney-papillary and stomach cancer), CYP11A1 (bladder, brain, kidney-clear and uterus cancer) and CCNB1 (brain, kidney-papillary, lung-adeno and lung-squamous cancer). The gene discussed is CYP11A1; the disease is uterine cancer.