Sil increased the levels of RBP4 and reduced the levels of IL-7, YKL 40, and PAI-1 in the liver (p < 0.05, Table 3), but only reduced the levels of YKL 40 and PAI-1 in the serum of mice with alcohol-induced acute liver injury (p < 0.05, Table 3). The gene discussed is SERPINE1; the disease is alcohol drinking.