The results also showed a number of genes that decreased in an Mn dose-dependent manner which include genes involved in iron transport (TF), protective activity of telomeres (TERF2), neurosensory function (MYO15a, OR1F1), and neurological disease such as ADHD (DIRAS2) and Parkinson’s disease (FRK). This evidence concerns the gene DIRAS2 and attention deficit-hyperactivity disorder.