Although five genomewide association studies (GWAS) of DKD identified several susceptible loci (Iyengar et al., 2015; Lim et al., 2017; Gurung et al., 2018; van Zuydam et al., 2018; Ahluwalia et al., 2019; Guan et al., 2019), no near loci linked to ACTB were observed as well as the data from GWAS of the National Human Genome Research Institute (https://research.nhgri.nih.gov/). The gene discussed is ACTB; the disease is diabetic kidney disease.