Colorectal cancer, triple negative breast cancer, Pancreatic cancer, non-small cell lung cancer, Head and neck cancer, Ovarian cancer, Lymphoma, sarcoma, Bladder cancer, Melanoma, IDH1 Mutated solid tumors, IDH1 Mutated or MGMT methylated recurrent HGG (Not Recruiting). The gene discussed is MGMT; the disease is colorectal cancer.