Colorectal cancer, triple negative breast cancer, Pancreatic cancer, non-small cell lung cancer, Head and neck cancer, Ovarian cancer, Lymphoma, sarcoma, Bladder cancer, Melanoma, IDH1 Mutated solid tumors, IDH1 Mutated or MGMT methylated recurrent HGG (Not Recruiting). This evidence concerns the gene IDH1 and familial pancreatic carcinoma.