ESR2 and lentivirus infection: On the other hand, SOD2 protein decreased to 51% as a result of HG(4d)+LG(4d) treatment compared to the LG(8d) group, and the lentivirus infection of either ERβ (↑ERβ) or SOD2 (↑SOD2), or ERβ agonist (DPN) treatment, increased SOD2 protein level by 169, 194, and 176%, respectively.