Again, infection of either ERβ lentivirus (HG(4d)+LG(4d)/↑ERβ), or SOD2 lentivirus (HG(4d)+LG(4d)/↑SOD2), or treatment with 100μM ERβ agonist (HG(4d)+LG(4d)/↑DPN) on day 4 completely restored 3-NT generation to normal (see Figure 1B). The gene discussed is ESR2; the disease is infection.