ESR2 and infection: It showed that ERβ binding ability decreased to 58% as a result of HG(4d)+LG(4d) treatment compared to the LG(8d)) group, and this was completely restored by either infection of ERβ lentivirus (↑ERβ) or SOD2 lentivirus (↑SOD2), or ERβ agonist (DPN) treatment.