Tables 2, 3 present the characteristics of obese and non-obese subjects with and without T2D. Leptin was significantly increased in obese subjects compared to non-obese subjects, regardless of T2D status. Table 4 presents the characteristics of non-obese non-T2D, obese non-T2D, and obese T2D subjects. This evidence concerns the gene LEP and type 2 diabetes mellitus.