LRRK2 and Parkinson disease: Second, the increased risk of psoriasis in overweight individuals (97–100), and the increased risk of CD in carriers of certain LRRK2 alleles (101, 102) are most simply explained by enhanced lipid availability (103) which promotes Malassezia's growth by supplying it with lipids [the same LRRK2 alleles increase PD risk (101, 102)].