Potential targets/approaches for alleviation of psychostimulant-induced impulsivity, memory impairment, and/or facilitation extinction of drug-associated memories. BDNF, brain-derived neurotrophic factor; CRF, corticotrophin-related factor; Trk B, tropomyosin-related kinase B; nACh, nicotinic acetylcholine; IGF, insulin growth factor; PAM, positive allosteric modulator; PPARγ, peroxisome proliferator agonist receptor gamma. The gene discussed is BDNF; the disease is memory impairment.