SORT1 and myocardial infarction: A series of genome-wide association studies showed that the minor allele of a common noncoding polymorphism at the 1p13 locus (rs12740374) creates a CCAAT/enhancer binding protein (C/EBP) TFBS and increases the hepatic expression of the SORT1 gene, reducing LDL-C levels and risk for myocardial infarction in humans38.