CD63 and cancer: The well-designed in vivo experiment also demonstrated that exosomes (labelled with CD63 (exosomes’ marker) fused red fluorescent) were derived from miR-940 overexpressed cancer cells and absorbed by host cells (labelled with GFP) under confocal microscopy, which caused osteoblastic lesions by implanting cancer cells onto the calvarial bones/tibial sites of immunodeficient mice [75].