Notably, a significant number of non-vascular CD34+ cells with round morphology were also identified in the spinal cord of ALS subjects but not in controls, with frequent CD34+ cells being localized in the proximity of apparent motor neuron cell bodies morphologically identified by typical shape, size, and localization in the ventral horn as described in other reports, and as shown in Figure 5C. CD34+ cells in ALS subjects were not grouped in clusters and only a subpopulation of CD34+ cells co-expressed Iba1, as shown in Figure 5D,E. Here, AIF1 is linked to amyotrophic lateral sclerosis.