The most numerous groups of drugs taken by the patients were medicines used in the treatment of hypertension, coronary heart disease, dyslipidaemia and hyperglycaemia: loop diuretics (29.96%), thiazide diuretics (6.1%), spironolactone (5.15%), angiotensin convertase inhibitors (17.46%), angiotensin receptor blockers (6.99%), alpha-adrenergic blockers (13.95%), beta-adrenergic blockers (52.02%), calcium channel blockers (31.25%), imidazoline receptor agonists (7.9%), insulin (15.26%), oral antidiabetic drugs (5.33%) and HMG-CoA reductase inhibitors (33.82%). The gene discussed is INS; the disease is coronary artery disorder.