SND1 and malignant colon neoplasm: miR-361 directly targeted SND1 (Staphylococcal nuclease and tudor domain containing 1), and SND1 conversely suppressed the expression of miR-361 by binding to pre-miR-361, thus creating a double-negative feedback loop, in which miR-361 and SND1 repress expression of each other in gastric and colon cancer cells [24].