The LPSs are endotoxins found in gram-negative bacteria related to the activation of the Toll-like receptor 4 (TLR4), which regulates the pro-inflammatory cytokines, and their increase in the blood circulation which can be related to dietetic factors such as the consumption of saturated fats, which stimulate the TLR4 receptors, inducing endotoxemia and inflammation [50]. Here, TLR4 is linked to serum lipopolysaccharide activity.