In a landmark study, Liu et al. reported that CD44+/CD24− CSCs resided at the edge of the breast tumor with low expression of E-cadherin but high expression of vimentin and ZEB1 (Zinc Finger E-Box Binding Homeobox 1), exhibiting a mesenchymal, migratory, and invasive phenotype [11]. Here, ZEB1 is linked to breast neoplasm.