The following adverse events occurred in the placebo group: four cases of common cold symptoms, one case of low back pain, one case of colonic polypectomy, one case of cerebral infarction (loss of fine movement of the right index finger and thumb), one case each of increased γ-GTP and uric acid levels, two cases of increased TG and CRP levels, three cases of increased CPK, and two cases of positive urinary protein. The gene discussed is CRP; the disease is brain infarction.