In an obese mouse model, supplementation with herb mixtures containing WEC decreased serum inflammatory cytokine levels and improved hyperglycemia and atherogenic lipid profile such as high triglycerides and low HDL-cholesterol via the inhibition of mRNA expression of hepatic fatty acid synthase and sterol regulatory element binding proteinsi-1c [57,58]. The gene discussed is FASN; the disease is Hyperglycemia.