A2M and diabetes mellitus: During the last decades, a great variety of multiparametric panels and parameter combinations (NFLS, HIS, FLI, LAP index, FLIP, CHeK, NFS, APRI, BARD, ELF, Hepascore) taking into account serum markers (e.g., ALT, AST, bilirubin, Hb1Ac, HDL, α2M, platelet counts), patient characteristics (sex, gender, BMI), or comorbidities (diabetes) were established.