CD274 and neoplasm: MSD assays measuring IP-10 induction were performed on murine PD-L1-expressing cancer cell lines, and although the nontargeted anti-TeTx-IFN-α fusion can induce IP-10 secretion from antigen positive tumor cells, the tumor targeting IFN-α was able to significantly increase IP-10 production at the same concentrations (Fig 2A).