Before 2012, in the early stage of epilepsy genetics research during the past decade, the most popular topic of research was of “sodium channels” and “Dravet syndrome” (cluster 1, with AAYs of 2011.5 and 2011.7 respectively); “SCN1A,” the most common genetic etiology associated with Dravet, had an AAY of 2013.5 with an occurrence of 399. Here, SCN1A is linked to encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.