GLRA1 and hyperekplexia: Hyperekplexia is a very rare neurological disorder characterized by exaggerated startle responses to unexpected stimuli, with a large spectrum of clinical severity (e.g. neonatal hypertonia, startle‐induced falls, intellectual disability).1 Hyperekplexia is caused by autosomal dominant or recessive modes of inheritance with more than 30 mutations reported in the alpha‐1 subunit of the glycine receptor gene, GLRA1,2 a ligand‐gated chloride channel that mediates postsynaptic inhibition mostly in the brainstem and spinal cord.