44 Caspi Caspi A A Sugden Sugden K K Moffitt Moffitt TE TE Taylor Taylor A A Craig Craig IW IW Harrington Harrington H H Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science Science 2003 2003 301 301 (5631) (5631) 386 386 389 389 12869766 12869766 44. The gene discussed is SLC6A4; the disease is major depressive disorder.