As shown in Fig. 1, there was an associated increase in IL1-β (Fig. 1B, P = 0.03), IL-6 (Fig. 1C, P = 0.001), CXCL1 (Fig. 1D, P = 0.001) and MCP-1 (Fig. 1E, P = 0.003) serum levels in malaria-infected mice, when compared to the control group, on GD18.5. This evidence concerns the gene IL6 and malaria.