[16] showed that MALAT1 induced the radioresistance of esophageal squamous cell carcinoma (ESCC) cells by down-regulating the expression of cdc kinase subunit 1 (CKS1), which is a regulatory protein that induces G2/M arrest by inhibiting p27 [17]. This evidence concerns the gene CKS1B and esophageal squamous cell carcinoma.