TERT and central nervous system cancer: To investigate the underlying oncogenic mechanisms of concomitant TERT promoter and BRAFV600E mutations in glioma, we analyzed the expression of different ETS-factors (ETS1, GABPA, GABPB-1S, GABPB-1 L, GABPB-2) and their downstream targets cyclin D1 and TERT in tissues of BRAFV600E-positive glioma (n = 8) (Additional file 3: Figure S1).