They found the genes with alternative isoforms can be detected in all the tested cancer cell lines (Cyclin D1, DICER1 and RAB10), or in at least a third of the samples (IMP-1, Cyclin D2 and FGF2), and shorter mRNAs were detectable and more prominent in these cancer cell lines compared to normal tissues. The gene discussed is CCND1; the disease is cancer.