NR4A1 and metastatic colorectal cancer: For example, Tran et al. infused a dose of 1.48 × 1011 TILs to a patient with metastatic colorectal cancer [35] and Zacharakis et al. described infusion of 8.2 × 1010 TILs to a patient with chemorefractory hormone receptor-positive metastatic breast cancer [36].