Figure 6 summarizes the diseases with a threshold association score > 0.001 for each gene (see Additional file 6: for a complete list); only SFXN2 had not been previously significantly associated with any disease in the database While the other genes have not been previously linked to AIS, they have been linked with diseases and comorbidities such as diabetes (ID3, SLC22A1), obesity (SLC22A1), and myocardial ischemia (ID3). The gene discussed is SFXN2; the disease is Obesity.