We also demonstrated that enforced SNHG1 expression was a predictor of worse outcome in digestive system (HR = 2.04, 95% CI: 1.56–2.68, P < 0.01) and non-digestive system (HR = 2.09, 95% CI: 1.55–2.83, P < 0.01) cancer patients. The gene discussed is SNHG1; the disease is cancer.