The combined results indicated that the elevated SNHG1 expression level was significantly predicted poor OS (HR = 2.06, 95% CI: 1.69–2.52, P < 0.01) and PFS (HR = 2.78, 95% CI: 1.69–4.55, P < 0.01) in various cancers. The gene discussed is SNHG1; the disease is cancer.