KEGG pathway analysis revealed that the DEGs were mainly enriched in focal adhesion, human papillomavirus infection, ECM − receptor interaction, protein digestion and absorption, small cell lung cancer, arginine and proline metabolism, PI3K-Akt signaling pathway, dilated cardiomyopathy (DCM), valine, leucine and isoleucine degradation, cell cycle (Fig. 4). The gene discussed is AKT1; the disease is human papilloma virus infection.