Decreased phosphorylated AMPKα levels, typically observed in AAA patients, could be restored in mice infused with Angiotensin-II, using aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR), a specific activator of the AMPK pathway, or metformin, a drug currently used in the treatment of Type II diabetes [107]. Here, AGT is linked to triple-A syndrome.