To evaluate the role of NEDD4‐1 in the sensitivity of MM cells to Bor, we altered NEDD4‐1 expression by transfecting HMCLs with NEDD4‐1 short hairpin RNAs (shRNAs) for KD experiments or HA‐NEDD4‐1 lentivirus vectors for OE experiments (Fig. 2c, Supporting Information Figs. S1f and S1g). This evidence concerns the gene NEDD4 and Miyoshi myopathy.