CXCL12 and breast carcinoma: Nishita et al showed that stromal cell‐derived factor 1 (SDF‐1) stimulated Jurkat T‐cell chemotaxis by activating RAC1/LIMK1/cofilin pathway, and suppression of LIMK1 greatly inhibited pseudopodia extension and T‐cell movement.39 LIMK1 also enhanced pseudopodia formation and cell migration in PCa40 and breast cancer,41 which were similar to the findings of this study.