The results demonstrated that knocking down RAC2/PAK4 with siRNA pool reproduced the antiproliferative, mitosis‐obstructive, and antimigratory effects of miR‐608 overexpression in PCa cells (Figures 6 and 7), and knocking down BCL2L1 with siRNA pool reproduced the proapoptotic effect of miR‐608, which also involved caspase‐3 activation (Figure 6F‐I). Here, PAK4 is linked to posterior cortical atrophy.