The results demonstrated that knocking down RAC2/PAK4 with siRNA pool reproduced the antiproliferative, mitosis‐obstructive, and antimigratory effects of miR‐608 overexpression in PCa cells (Figures 6 and 7), and knocking down BCL2L1 with siRNA pool reproduced the proapoptotic effect of miR‐608, which also involved caspase‐3 activation (Figure 6F‐I). This evidence concerns the gene RAC2 and posterior cortical atrophy.