Suppression of miR‐124 expression could inhibit GC proliferation and invasion via binding with the SPHK1 3'‐UTR in MGC‐803 cells.72 Liu et al found that miR‐124‐3p was involved in the carcinogenesis of GC (SGC‐7901 and MKN‐28) by dual‐targeting Rac1 and Sp1.73 Mirnoori et al first announced that the overexpression of pri‐miR‐124‐1 caused STAT3 mRNA level reduction and STAT3 phosphorylation. The gene discussed is SPHK1; the disease is gastric cancer.