IQGAP1 and colorectal carcinoma: At the same time, overexpressed miR‐124 could induce apoptosis of CRC cells and inhibit the growth of tumors by targeting STAT3 and regulating its downstream signaling.77 In addition, miR‐124 could combine with the 3'‐UTR of the IQ motif containing GTPase‐activating protein 1 (IQGAP1).