The scatterplot in Fig. 5 shows that most PID cases had damaging variants with a high MRF score, while PID cases carried benign variants in RAG1/2 with lower MRF scores, i.e., an MRF > 0.04 was seen for 31 cases of a damaging variant and only 2 cases of a non-damaging variant. The gene discussed is RAG1; the disease is pelvic inflammatory disease.