CRP and endometriosis: One likely reason that this study has underestimated variation is that there may be non-EOC conditions, much more frequently occurring than EOC, but sufficiently rare as to have been excluding from this control set, that affect PROZ, LCAT and CRP levels just endometriosis and the menstrual cycle do for CA125.24,25 Analysis of the longitudinal behaviour of these proteins in a much larger cohort of control women is required to obtain more precise estimates of specificity and PPV.