At the COMMD10 locus, rs12520838 was associated with PAD in MESA Hispanics (p = 7.5 × 10−5), a SNP that is 99,000 base-pairs away from the HCHS/SOL Puerto Rican lead variant (rs4466200); these variants are not in LD, as estimated in the HCHS/SOL. The gene discussed is COMMD10; the disease is peripheral arterial disease.