APS-MNPs attached to the cell membrane of adoptively transferred OT-I CD8+ T cells together with the application of an EMF in close proximity to the tumour during cell transfer reduced the infiltration of these transferred cells into the tumoral region but simultaneously promoted the retention of activated tumour-specific OT-I CD8+ T cells in the tumour-draining lymph nodes. The gene discussed is CD8A; the disease is neoplasm.